HCID 18521858, compound → HCID 18521783, compound

HRID 413733Notes

Reaction equation

HRID 413733 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]([C:12]2[S:16][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[N:14][C:13]=2[NH2:24])=[O:11])=[CH:6][CH:5]=1)([O-])=O>C(O)C>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([C:10]([C:12]2[S:16][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[N:14][C:13]=2[NH2:24])=[O:11])=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 18521858HCID 18521858, compound

Product 1

HCID 18521783HCID 18521783, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound was prepared in a manner like that described for Example D(1). Catalytic reduction of the title compound of Example A(2) ((4-nitro-phenyl)-(4-amino-2-phenylamino-thiazol-5-yl)-methanone) provided, after recrystallization from ethanol, 410 mg (90% yield) of red amorphous powder, mp >300° C.

Workup

  1. customThe title compound was prepared in a manner like that

Sources & evidence

ORD record
ord-a4f6aacb2a12482c94e30ad8a13bff44
Source dataset
uspto-grants-2003_05
Patent number
US06569878B1

Reaction notes

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