Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Difluorophenyl isocyanate → (N'-((2,6-Difluorophenyl)aminocarbonyl)-L-alaninyl]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Difluorophenyl isocyanate | HCID 522162 | — |
| 반응물 | (S)-3-[(L-alaninyl)]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 20589655 | — |
| 생성물 | (N'-((2,6-Difluorophenyl)aminocarbonyl)-L-alaninyl]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 86758989 | — |
반응 단계
Following General Procedure (5-A1) using 2,6-difluorophenyl isocyanate and (S)-3-[(L-alaninyl)]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one, as described in Example 8-B above, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: 491 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06569851B1 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-93bac062ff23434aa8aab549aeadf6fd |
| 출처 메모 | uspto-grants-2003_05 |