HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isocyanatothiophene → (N'-((2-(2-Thiophene-yl)ethyl)aminocarbonyl)-L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isocyanatothiophene | HCID 2776375 | — |
| Reactant | 3-(L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 23552762 | — |
| Product | (N'-((2-(2-Thiophene-yl)ethyl)aminocarbonyl)-L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 86758990 | — |
Reaction Steps
Following General Procedure (5-A1) using 2-thiophene-yl isocyanate and 3-[(L-alaninyl)]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one, as described in Example 8-B above, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06569851B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-27f66d695ede4faa98323d6d95b1e560 |
| Source note | uspto-grants-2003_05 |