2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 136116400, compound

Participants

Reaction Steps

A mixture of 5-ethyloxycarbonyl-2-methylthio-4-phenyl-4,5-dihydro-6-oxopyrimidine (273 mg) and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (200 mg) in isopropanol (5 ml) was stirred for 16 h. The reaction mixture was evaporated to dryness, the residue was dissolved in dichloromethane and stirred with 5% sodium thiosulfate for 5 min. The organic layer was washed with 5% sodium bicarbonate and water (2×), dried over sodium sulfate and evaporated to dryness. The pure title compound was obtained after chromatography on silicagel in dichloromethane/methanol 98/2 (v/v) as eluent.

Provenance & Evidence