Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Peroxide → 3-Chloro-2-pyridinesulfonamide-1-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | 3-Chloropyridine-2-sulfonamide | HCID 14653191 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | 3-Chloro-2-pyridinesulfonamide-1-oxide | HCID 14653192 | — |
반응 단계
To a stirring solution of 3-chloro-2-pyridinesulfonamide (2.5 g, 13.0 mmol) in 35 mL of trifluoroacetic acid was added 30% H2O2 (1.2 g, 35.1 mmol). The solution was concentrated to ~15 mL, diluted with ethyl acetate, washed twice with brine, dried and concentrated. The resulting solid was flash chromatographed with EtOAc to afford the desired product, m.p. 195°-197° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04789465 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-f666cba1e83b4b27a01b856d53dc4028 |
| 출처 메모 | uspto-grants-1988_12 |