Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,4-Trimethylpentane → 3,5-dichloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,4-Trimethylpentane | HCID 10907 | — |
| 반응물 | Benzamide, 3,5-dichloro-2,6-dimethoxy-N-(1-ethyl-2-pyrrolidinylmethyl)- | HCID 54941 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3,5-dichloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide | HCID 5118 | 37% |
반응 단계
The title compound was prepared from (-)-N-ethyl-2-(3,5-dichloro-2,6-dimethoxybenzamidomethyl)pyrrolidine by dealkylation in the same manner as described in Example 2. Yield 37%. M.p. 48°-49° C. (i-octane). [α]D25 =-64° C. (c=1.26; CHCl3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04789683 |
| 출처 데이터셋 | uspto-grants-1988_12 |
| ORD ID | ord-611965bfa22442ada288636db728707e |
| 출처 메모 | uspto-grants-1988_12 |