HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 1-Chloro-2-(chloromethyl)-3-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | 2-Chloro-6-fluorotoluene | HCID 9933 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Product | 1-Chloro-2-(chloromethyl)-3-fluorobenzene | HCID 108675 | — |
Reaction Steps
The starting material may be prepared as follows: A mixture of 98 g (0.678 mole) of 6-chloro-2-fluorotoluene, 91.5 g (0.678 mole) of sulfuryl chloride and 0.2 g of dibenzoyl peroxide is stirred for 3 hours at 100°-110° C. and then distilled, affording 6-chloro-2-fluorobenzyl chloride with a boiling point in the range from 78°-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04789680 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-4b91bd34267c42739eb7184dafbe1c6f |
| Source note | uspto-grants-1988_12 |