HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → N-Formyl-L-tyrosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | L-Tyrosine | HCID 6057 | — |
| Product | N-Formyl-L-tyrosine | HCID 13025455 | — |
Reaction Steps
Under a nitrogen atmosphere, a slurry of 1.81 gm (10 mmol) tyrosine in 4.0 ml (100 mmol) formamide was heated at 90° C. for 19 hours and 10 minutes. Examination of the resulting homogeneous solution by proton NMR showed an 84% conversion of the tyrosine to its N-formyl derivative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04789757 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-4842c3cd3bd64d55beae526ac76570de |
| Source note | uspto-grants-1988_12 |