Boron tribromide → HCID 57211300, compound

HRID 414185Notes

Reaction equation

HRID 414185 reaction equation
[CH:1]1([CH2:4][N:5]2[C@@H:9]3[N:10]([CH3:19])[C:11]4[C:16]([C@:8]3([CH3:20])[CH2:7][CH2:6]2)=[CH:15][C:14]([O:17]C)=[CH:13][CH:12]=4)[CH2:3][CH2:2]1.B(Br)(Br)Br>C(Cl)(Cl)Cl>[CH:1]1([CH2:4][N:5]2[C@@H:9]3[N:10]([CH3:19])[C:11]4[C:16]([C@:8]3([CH3:20])[CH2:7][CH2:6]2)=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=4)[CH2:2][CH2:3]1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 22840862(3aS-cis)-1-cyclopropylmethyl-1,2,3,3a,8,8a-hexahydro-5-methoxy-3a,8-dimethylpyrrolo[2,3-b]indole

Product 1

HCID 57211300HCID 57211300, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound is prepared in the same manner as described for the 1-(2-phenylethyl) analog of Example 45 except that 2.72 g of (3aS-cis)-1-cyclopropylmethyl-1,2,3,3a,8,8a-hexahydro-5-methoxy-3a,8-dimethylpyrrolo[2,3-b]indole is reacted as a starting material with 10.1 g of boron tribromide in chloroform.

Sources & evidence

ORD record
ord-534ada218f6d4cf8824a3f81d4b3170c
Source dataset
uspto-grants-1988_12
Patent number
US04791107

Reaction notes

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