Pyridine N-Oxide → HCID 13961163, compound

Participants

Reaction Steps

A solution of 3.84 g (0.02 mole) of 5,6-dimethyl-2-mercaptomethylbenzimidazole and 1.9 g (0.02 mole) of pyridine N-oxide in 50 ml of acetic anhydride is heated to 100° C. for 4 hours. The acetic anhydride is evaporated off, the residue taken up with acetone and the mixture filtered and concentrated to a volume of 20 ml. From this solution, 2.6 g (48%) of 5,6-dimethyl-2-(2-pyridylthiomethyl)benzimidazole crystallize. The product thereby obtained is identical to that obtained by Method A, and the data for the identification appear in Tables 1 and 2.

Provenance & Evidence