反应详情

Twenty g. of 3,6-dichloropyridazine was alkylated with 44.4 g. of 2-methyl-2-propyl-1,3-propanediol, following the process of Preparation 3 above. In this case the chromatography was run with 3:1 heptane:ethyl acetate as the eluant, and the residue from evaporation of the combined product-containing fractions was recrystallized from diethyl ether/heptane to obtain 0.43 g. of the desired intermediate product, m.p. 99°-100°.

1. customthe process of Preparation 3 above
2. customethyl acetate as the eluant, and the residue from evaporation of the
3. additioncombined product-containing fractions
4. customwas recrystallized from diethyl ether/heptane
5. customto obtain 0.43 g