HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 6-[(4"-Aminobenzoyl)azo]-8-{[(aminocarbonyl)oxy]methyl}-4,7-dihydroxy-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Mitomycin A | HCID 19972 | — |
| Reactant | 4-Aminobenzoic acid hydrazide | HCID 21450 | — |
| Product | 6-[(4"-Aminobenzoyl)azo]-8-{[(aminocarbonyl)oxy]methyl}-4,7-dihydroxy-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a)indole | HCID 136342835 | 40.5% |
Reaction Steps
In a similar manner to that described in Example 17, mitomycin A (302 mg), 4-aminobenzoylhydrazine (389 mg) and potassium carbonate (150 mg) are used to obtain the desired product (163 mg) with a yield of 40.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04791113 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-f43c1da2a11c473abcc24aaa81d56c1c |
| Source note | uspto-grants-1988_12 |