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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 414359Generated: October 29, 2026

Methyl 2-pentenoate → Methyl 3-methoxyvalerate

https://huagongshe.com/reaction/414359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-pentenoateHCID 5364718—
Reactantmethyl (Z)-pent-2-enoateHCID 6197811—
ReactantSodium MethoxideHCID 10942334—
SolventMethanolHCID 887—
ProductMethyl 3-methoxyvalerateHCID 126363442,998.3%

Reaction Conditions

Temperature65 °C

Reaction Steps

A solution of 5.4 g of sodium methylate in 64 g of methanol was added to a mixture of 192 g of methyl cis trans-3-pentenoate, 4 g of methyl 2-cis-pentenoate and 28 g of methyl 2-trans-pentenoate, and the mixture was heated to 65° C. and stirred for four hours at this temperature. After the working up procedure described in Example 1, 153.6 g (53% of theory) of methyl 3-methoxyvalerate were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04791219
Source datasetuspto-grants-1988_12
ORD IDord-a26af50954704d73947f3d679bc0d754
Source noteuspto-grants-1988_12