Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Methyl 2-pentenoate | HCID 5364718 | — |
| Product | Methyl 3-piperazinovalerate | HCID 20035198 | 51.8% |
Reaction Steps
A mixture of 213 g of methyl 2-trans-pentenoate and 64 g of piperazine was stirred for 44 hours at 60° C. Fractional distillation gave 77.1 g of methyl 3-piperazinovalerate of boiling point 105° C./0.4 mbar, nD20 =1.4740, the yield being 51%, based on piperazine used. delta =0.70-1.80 (m, 5 H), 1.72 (s, 1 H), 2.0-3.2 (m, 11 H), 3.70 ppm (s, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04791220 |
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| Source dataset | uspto-grants-1988_12 |
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| ORD ID | ord-017697635df9482592b219a0c0269f5e |
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| Source note | uspto-grants-1988_12 |
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