HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1,3-propanediol → 2-[(5-Naphthacenylmethyl)amino]-2-methyl-1,3-propanediol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1,3-propanediol | HCID 1531 | — |
| Reactant | 5-Naphthacenecarboxaldehyde | HCID 11149531 | — |
| Solvent | Diethyl ether ethanol | HCID 21585056 | — |
| Product | 2-[(5-Naphthacenylmethyl)amino]-2-methyl-1,3-propanediol | HCID 149310 | 50.1% |
Reaction Steps
Using the reductive amination procedure described in Example 1, naphthacene-5-carbaldehyde (3A) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 50.1% yield of 2-[(5-naphthacenylmethyl)amino]-2-methyl-1,3-propanediol methanesulfonte, mp 197.5°-199°, (EtOH/Et2O), (C, H, N, S).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04791233 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-7f92b10e828e4e9b99a59650590194cc |
| Source note | uspto-grants-1988_12 |