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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 414445Generated: October 25, 2026

Formaldehyde → 2-(Aminomethyl)phenol

https://huagongshe.com/reaction/414445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantPhosphoric AcidHCID 1004—
Reactant4-tert-ButylphenolHCID 7393—
Reactant3-Amino-1-propanolHCID 9086—
SolventWater ethanolHCID 19096565—
Product2-(Aminomethyl)phenolHCID 70267—

Reaction Steps

An o-hydroxybenzylamine compound of the present invention composition is prepared according to the procedure of Example 1, except that 50 g of 4-t-butylphenol is employed in place of the Bisphenol-A, 25 g of 3-aminopropanol is employed in place of the 2-(methylamino)ethanol and that heating of the reactants was only begun after the formaldehyde addition was completed. A 0.5 g sample of the product is dissolved in 500 ml of ethanol/water (1:4 by volume) and the pH of the solution is adjusted to 3.0 with phosphoric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04792355
Source datasetuspto-grants-1988_12
ORD IDord-9c1e391366f54a0e8e4a538accb81608
Source noteuspto-grants-1988_12