反应详情

温度

176 °C

p-Cresol (1.2 g, 0.01 mole), para-(methylthio)phenol (3.0 g, 0.02 mole), and H ELZ-20 from Example 27 (1.0 g) were combined and heated at 176° C. for 14 hours. The mixture was cooled to room temperature and filtered. The catalyst was washed several times with ether. The filtrate and ether washings were combined, and volatiles were removed on a rotary flash evaporator. GC analysis indicated the presence of 2-methylthio-4-methylphenol (0.9 g, 56% yield).

1. temperatureThe mixture was cooled to room temperature
2. filtrationfiltered
3. washThe catalyst was washed several times with ether
4. customvolatiles were removed on a rotary flash evaporator