4-Methyl-6-nitro-7-hydroxy-1-indanone → 6-Amino-4-methyl-7-hydroxy-1-indanone

Participants

Reaction Steps

Into a solution of 26.0 g of 4-methyl-6-nitro-7-hydroxy-1-indanone in 50 ml of dimethylformamide was added 2.6 g of 10% palladium carbon, then the mixture was subjected to a catalytic hydrogenation under an atmospheric pressure at 0° C. to a room temperature. The catalyst was removed by filtration and the solvent was removed by evaporation to obtain 17.3 g of 6-amino-4-methyl-7-hydroxy-1-indanone.

Provenance & Evidence