反应详情

Into a solution of 11.5 g of 4-methyl-6-nitro-7-hydroxy-1-indanone in 500 ml of acetic acid was added 1.5 g of 5% palladium carbon, then the mixture was subjected to a catalytic hydrogenation under an atmospheric pressure at a room temperature. The catalyst was removed by filtration and the solvent was removed by evaporation. The residue obtained was washed with ether and was recrystallized from methanol to obtain 6.34 g of 4-methyl-6-acetamido-7-hydroxy-1-indanone.

1. customwas subjected to a catalytic hydrogenation under an atmospheric pressure at a room temperature
2. customThe catalyst was removed by filtration
3. customthe solvent was removed by evaporation
4. customThe residue obtained
5. washwas washed with ether
6. customwas recrystallized from methanol