3-(5-Nitrofuran-2-yl)prop-2-enal → Imidazo[2,1-b]thiazole-6-carboxylic acid [(5-nitro-2-furyl)-2-propen1-ylidene]hydrazide

HRID 414710Notes

Reaction equation

HRID 414710 reaction equation
[N+:1]([C:4]1[O:8][C:7]([CH:9]=[CH:10][CH:11]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[S:13]1[CH:17]=[CH:16][N:15]2[CH:18]=[C:19]([C:21]([NH:23][NH2:24])=[O:22])[N:20]=[C:14]12>CO>[N+:1]([C:4]1[O:8][C:7]([CH:9]=[CH:10][CH:11]=[N:24][NH:23][C:21]([C:19]2[N:20]=[C:14]3[N:15]([CH:18]=2)[CH:16]=[CH:17][S:13]3)=[O:22])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 158633-(5-Nitrofuran-2-yl)prop-2-enalHCID 14098872Imidazo[2,1-b]thiazole-6-carbohydrazide

Product 1

HCID 54412069Imidazo[2,1-b]thiazole-6-carboxylic acid [(5-nitro-2-furyl)-2-propen1-ylidene]hydrazide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

According to the same procedure as in Example 1.2., 1.1 g (0.065 mole) of 3-(5-nitro-2-furyl)-2-propenal and 1.2 g of imidazo[2,1-b]-thiazole-6-carbohydrazide are reacted in methanol. The compound, melting point 332° C., is obtained.

Workup

  1. customThe compound, melting point 332° C., is obtained

Sources & evidence

ORD record
ord-5fd36b8092af4c08987d015958d7dff3
Source dataset
uspto-grants-1988_12
Patent number
US04794120

Reaction notes

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