HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-Chloro-1-[2-[4-ethylthio-3-methylpyridyl)-2-oxoethyl]benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Reactant | 2-Bromoacetyl-4-ethylthio-3-methylpyridine | HCID 14421553 | — |
| Product | 2-Chloro-1-[2-[4-ethylthio-3-methylpyridyl)-2-oxoethyl]benzimidazole | HCID 14421554 | — |
Reaction Steps
2-Chlorobenzimidazole is reacted with 2-bromoacetyl-4-ethylthio-3-methylpyridine in the presence of K2CO3 to give 2-chloro-1-[2-[4-ethylthio-3-methylpyridyl)-2-oxoethyl]benzimidazole. This is reacted with thiourea and treated with NH4OH to give 2-mercapto-1-(2-(2-(4-ethylthio-3-methylpyridyl))-2-oxoethyl)benzimidazole
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04794123 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-7df36b48005c477db4c2d7b60163a2ad |
| Source note | uspto-grants-1988_12 |