HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-(Tetrazol-1-yl)-valeric acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-(1H-Tetrazol-1-yl)pentanoic acid | HCID 21280290 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 5-(Tetrazol-1-yl)-valeric acid chloride | HCID 17803406 | — |
Reaction Steps
1 g of 5-(tetrazol-1-yl)-valeric acid in 12 ml of absolute benzene is heated at reflux temperature for 20 minutes with 0.6 ml of thionyl chloride and 2 drops of DMF. After concentration by evaporation under reduced pressure, the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04794109 |
| Source dataset | uspto-grants-1988_12 |
| ORD ID | ord-32e5de1ea3664904b0df90faaf844a44 |
| Source note | uspto-grants-1988_12 |