HCID 70418165, compound → HCID 70417273, compound

Participants

Reaction Steps

In 50 ml of methanol is dissolved 1.83 g (5 mmole) of trans-1-benzyloxy-3-(tert-butoxycarbonylamino)-4-carbamoyloxymethyl-2-azetidinone, and 190 mg of 10% palladium-charcoal is added to the solution, followed by stirring under a hydrogen atmosphere at room temperature for 30 minutes. The catalyst is filtered off, and the filtrate is concentrated under reduced pressure to give 1.32 g (96.1%) of trans-3-(tert-butoxycarbonylamino)-4-carbamoyloxymethyl-1-hydroxy-2-azetidinone as a colorless foamy product.

Provenance & Evidence