HCID 70418273, compound → HCID 70417468, compound

Participants

Reaction Steps

In 200 ml of methanol is suspended 3.69 g (11 mmole) of trans-1-benzyloxy-3-(tert-butoxycarbonylamino)-4-carbamoyl-2-azetidinone, and 350 mg of 10% palladium-charcoal is added to the suspension, followed by stirring under a hydrogen atmosphere at room temperature for 30 minutes. The catalyst is filtered off, and the filtrate is concentrated to dryness under reduced pressure to give 2.7 g of trans-3-(tert-butoxycarbonylamino)-4-carbamoyl-1-hydroxy-2-azetidinone as a yellowish foamy product.

Provenance & Evidence