HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid → methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid hydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid | HCID 66646296 | — |
| Solvent | Water | HCID 962 | — |
| Product | methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid hydrate | HCID 68821413 | — |
Reaction Steps
When water is added, the amount of water used is preferably 0.1 to 10 times (v/w) the amount of methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid. More particularly, the third crystals of methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid hydrate can be produced by the method described in Example 6 below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530654B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-223a9d6560af43faace9cf06f094f861 |
| Source note | uspto-grants-2013_09 |