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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 414920Generated: October 30, 2026

Hydrochloric Acid → HCID 66624139, compound

https://huagongshe.com/reaction/414920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 44234055HCID 44234055—
SolventMethanolHCID 887—
SolventIsopropanolHCID 3776—
SolventDichloromethaneHCID 6344—
ProductHCID 66624139HCID 66624139—

Reaction Steps

100 mg of [4-[(2-quinolin-3-yl)imidazo[1,2-a]pyridin-6-yl]thien-2-yl]methanol are suspended in dichloromethane and methanol. The solution is passed through a frit and 5.6 ml of a 0.1N solution of hydrochloric acid in isopropanol are added to the filtrate. The reaction mixture is then concentrated under reduced pressure and the residue is then taken up in diethyl ether. The precipitate is recovered by filtration and oven-dried under reduced pressure. 106 mg of compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088765B2
Source datasetuspto-grants-2012_01
ORD IDord-29aa95229bf94c9ab0f6c9fa65e31c43
Source noteuspto-grants-2012_01