HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylamine → 2-(3-Chlorobenzyl)-6-oxo-4-(propylamino)-1,6-dihydropyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | 2-(3-Chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile | HCID 58407802 | — |
| Product | 2-(3-Chlorobenzyl)-6-oxo-4-(propylamino)-1,6-dihydropyrimidine-5-carbonitrile | HCID 135995006 | — |
Reaction Steps
In analogy to the preparation of Example 1, 100 mg (0.34 mmol) of 2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 203 mg (3.43 mmol) of n-propylamine to give 12 mg (12% of theory) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088769B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d506f5c8116c4d91a53dc00e96965c69 |
| Source note | uspto-grants-2012_01 |