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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 414978Generated: October 30, 2026

Cyclopentylamine → HCID 135995046, compound

https://huagongshe.com/reaction/414978

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentylamineHCID 2906—
Reactant4-(Methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrileHCID 58407942—
ProductHCID 135995046HCID 135995046—

Reaction Steps

In analogy to the preparation of Example 1, 150 mg (0.57 mmol) of 4-(methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile are reacted with 485 mg (5.70 mmol) of cyclopentylamine to give 46 mg (26% of theory) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088769B2
Source datasetuspto-grants-2012_01
ORD IDord-97e496bd5391407391700feda754484d
Source noteuspto-grants-2012_01