HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanobenzaldehyde → [4-(Aminomethyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanobenzaldehyde | HCID 66042 | — |
| Reactant | [3,5-Bis(benzyloxy)benzyl]amine hydrochloride | HCID 15505554 | — |
| Product | [4-(Aminomethyl)phenyl]methanol | HCID 6496943 | 46% |
Reaction Steps
This compound was prepared by reduction of 4-cyanobenzaldehyde according to the procedure described in preparation of 3,5-dibenzyloxybenzylamine. Yield was 46%: MP 102-123° C.; 1H NMR (Acetone-d6, 500 MHz) 7.27 (m, complex 4H), 4.58 (s, 2H), 3.72 (s, 2H), 3.69 (s, 1H) 2.77 (br, 1H), 2.45 (br, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088768B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b23eafa848ec41ec93649b392dfe34a0 |
| Source note | uspto-grants-2012_01 |