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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 415137Generated: October 25, 2026

3-Hydroxyanthranilic Acid → 2-(1-(Benzyloxycarbonyl)-2-methylpyrrolidin-2-yl)benzo[d]oxazole-4-carboxylic acid

https://huagongshe.com/reaction/415137

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxyanthranilic AcidHCID 86—
ReactantBenzyl 2-(chlorocarbonyl)-2-methylpyrrolidine-1-carboxylateHCID 86633083—
Product2-(1-(Benzyloxycarbonyl)-2-methylpyrrolidin-2-yl)benzo[d]oxazole-4-carboxylic acidHCID 66620583—

Reaction Steps

2-(1-(Benzyloxycarbonyl)-2-methylpyrrolidin-2-yl)benzo[d]oxazole-4-carboxylic acid is prepared from 3-hydroxyanthranilic acid and benzyl 2-(chlorocarbonyl)-2-methylpyrrolidine-1-carboxylate using the conditions described in Example 3A. MS (ESI) m/e 381 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088760B2
Source datasetuspto-grants-2012_01
ORD IDord-68cbbc39ef854dfc8bdd95a5c69e7318
Source noteuspto-grants-2012_01