HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminosalicylic acid → 2-(4-(((Benzyloxycarbonyl)(methyl)amino)methyl)phenyl)benzo[d]oxazole-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminosalicylic acid | HCID 68443 | — |
| Reactant | Benzyl 4-(chlorocarbonyl)benzyl(methyl)carbamate | HCID 86633082 | — |
| Product | 2-(4-(((Benzyloxycarbonyl)(methyl)amino)methyl)phenyl)benzo[d]oxazole-7-carboxylic acid | HCID 66621286 | — |
Reaction Steps
2-(4-(((Benzyloxycarbonyl)(methyl)amino)methyl)phenyl)benzo[d]oxazole-7-carboxylic acid is prepared from 3-aminosalicylic acid and benzyl 4-(chlorocarbonyl)benzyl(methyl)carbamate using identical conditions described in Example 3A. MS (ESI) m/e 417 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088760B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-cf36b0e70f99439289a1fac7c2512d44 |
| Source note | uspto-grants-2012_01 |