HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → Methyl 4-[(methylamino)methyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| Reactant | Methylamine ethanol | HCID 22028356 | — |
| Product | Methyl 4-[(methylamino)methyl]benzoate | HCID 11194668 | 74.4% |
Reaction Steps
Methyl 4-(bromomethyl)benzoate was dissolved in methylamine ethanol solution and the mixture was stirred at reflux for 3 hr. The mixture was condensed under vacuum and poured into ethyl acetate and filtered. The cake was dried to get methyl 4-((methylamino)methyl)benzoate (2.5 g, 74.4%), LC-MS (ESI) m/e 180 [M+1]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088760B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-163fb8e25e924cd9b56f6f6711c3faf3 |
| Source note | uspto-grants-2012_01 |