p-Toluenesulfonic acid → HCID 66621176, compound

Participants

Reaction Steps

3-Hydroxy-2-(3-nitrobenzeneamido)benzoic acid (1.8 g, 6.0 mmol) and 4-methylbenzenesulfonic acid (2 g, 12.0 mmol) were added to toluene (36 mL) and the mixture was stirred under reflux for 10 hr. The solvents was evaporated under reduced pressure and the residue was washed with water (100 mL×3), filtered, the solid was dried in vacuum at 50° C. to obtain 2-(3-nitrophenyl)benzo[d]oxazole-4-carboxylic acid as a yellow solid (1.42 g, yield 83%). LC-MS (ESI) m/z 285 [M+1]+.

Provenance & Evidence