p-Toluenesulfonic acid → HCID 18354630, compound

Participants

Reaction Steps

3-Hydroxy-2-(4-nitrobenzamido)benzoic acid (1.8 g, 6.0 mmol) and 4-methylbenzenesulfonic acid (2 g, 12.0 mmol) were added to toluene (36 mL) and the mixture was stirred at reflux for 17 hr. The solvent was evaporated under reduced pressure and the residue was washed with water (100 mL×3), filtered and dried under reduced pressure at 50° C. to obtain a yellow solid of 2-(4-nitrophenyl)benzo[d]oxazole-4-carboxylic acid (1.42 g, yield 83%). LC-MS (ESI) m/z 285 [M+1]+.

Provenance & Evidence