Dimethylamine → Methyl 2-(4-((dimethylamino)methyl)phenyl)benzo[d]oxazole-7-carboxylate

Participants

Reaction Steps

To the solution of methyl 2-(4-(bromomethyl)phenyl)benzo[d]oxazole-7-carboxylate (150 mg, 0.72 mmol) in methanol (2 mL), was added dimethylamine solution (0.5 mL, 2.88 mmol), the resulting mixture was stirred at room temperature for 17 hr, then the solvents were evaporated and methyl 2-(4-((dimethylamino)methyl)phenyl)benzo[d]oxazole-7-carboxylate. LC-MS (ESI) m/z 311 [M+1]+.

Provenance & Evidence