Ammonia → HCID 46847386, compound

Participants

Reaction Steps

Methyl 2-(4-(pyridin-3-yl)phenyl)benzo[d]oxazole-7-carboxylate (150 mg, 0.45 mmol) was added to ammonia in methanol (30 mL) and the mixture was stirred at room temperature for 3 days. Then the solid was filtered, washed with methanol, dried in vacuum. 120 mg of 2-(4-(pyridin-3-yl)phenyl)benzo[d]oxazole-7-carboxamide was obtained. Yield: 84%. 1H-NMR (400 MHz, DMSO-d6) δ 7.52-7.58 (m, 2H), 7.83-8.05 (m, 6H), 8.21-8.23 (m, 1H), 8.42-8.44 (d, J=8 Hz, 2H), 8.64-8.66 (m, 1H); 9.03-9.04 (m, 1H); LC-MS (ESI) m/z: 316 (M+1)+.

Provenance & Evidence