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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 415390Generated: October 29, 2026

Ethanolamine → HCID 25109216, compound

https://huagongshe.com/reaction/415390

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantPhenyl 6-(2-fluoro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylateHCID 59259226—
ProductHCID 25109216HCID 25109216—

Reaction Steps

The title compound was synthesized following a similar procedure described in the synthesis of Example 5 by reaction of compound 2A and 2-aminoethanol. 1H NMR (400 MHz, CDCl3) δ ppm 3.10 (s, 3H) 3.39 (s, 3H) 3.53-3.57 (m, 2H) 3.78-3.81 (m, 2H) 6.81 (t, J=8.0 Hz, 1H) 7.47-7.52 (m, 2H) [M+H] calc'd for C15H16FIN4O4, 463; found, 463.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088783B2
Source datasetuspto-grants-2012_01
ORD IDord-de39c35d250b4cf2b088f61f629c6102
Source noteuspto-grants-2012_01