HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,6-dichloro-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine → 6-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,6-dichloro-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine | HCID 57556003 | — |
| Edukt | (S)-1-(5-Fluoropyrimidin-2-yl)ethanamine hydrochloride | HCID 66624037 | — |
| Produkt | 6-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine | HCID 50993803 | — |
Reaktionsschritte
Following a similar procedure to that of Example 9, the title compound was synthesized from 2,6-dichloro-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine (Method 17) and (5)-1-(5-fluoropyrimidin-2-yl)ethanamine hydrochloride (Method 7). m/z 348.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08088784B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-dc242424f50c4ff49f61c0766717b1dc |
| Quellennotiz | uspto-grants-2012_01 |