HCID 46830485, compound → HCID 46830486, compound

Participants

Reaction Steps

N-Benzyl-2-chloro-3-nitroquinolin-4-amine (31.9 g, 0.102 mol), 5% platinum on carbon (3.2 g), and acetonitrile (325 mL) were added to a Parr vessel and shaken under hydrogen pressure (30 psi, 2.1×105 Pa) overnight. The mixture was filtered through a layer of CELITE filter agent, and the filtrate was concentrated under reduced pressure and further dried under high vacuum to provide 27.82 g of N4-benzyl-2-chloroquinoline-3,4-diamine, which was used without purification.

Provenance & Evidence