反应详情

In steps (8) and (9) of Reaction Scheme IV, a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula LII is oxidized and then aminated to provide a 1H-imidazo[4,5-c]quinolin-6-amine or 1H-imidazo[4,5-c][1,5]naphthyridin-6-amine of Formula LIII, a subgenus of Formula I. The steps can be carried out using the methods described in steps (5) and (6) of Reaction Scheme I.