(2R)-propane-1,2-diamine dihydrochloride → HCID 136174526, compound

Participants

Reaction Steps

The methods described in Parts A through C of Example 23 were used to prepare (10R)-10-methyl-9,10-dihydro-8H-imidazo[1′,2′:1,2]imidazo[4,5-c]quinoline with (R)-(−)-1,2-diaminopropane dihydrochloride used in lieu of (S)-(−)-1,2-diaminopropane dihydrochloride in Part A. The methods described in Parts A through D of Example 27 were used to convert (10R)-10-methyl-9,10-dihydro-8H-imidazo[1′,2′:1,2]imidazo[4,5-c]quinoline to the title compound, which was obtained as a white solid, m.p. 272-274° C.

Provenance & Evidence