HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-(Trifluoromethyl)-1-benzothiophen-2-yl]methanol → 2,6-Difluoro-3-[5-(trifluoromethyl)-1-benzothiophen-2-yl]methoxybenzenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-(Trifluoromethyl)-1-benzothiophen-2-yl]methanol | HCID 36995549 | — |
| Reactant | 2,6-Difluoro-3-hydroxybenzamide | HCID 45120136 | — |
| Product | 2,6-Difluoro-3-[5-(trifluoromethyl)-1-benzothiophen-2-yl]methoxybenzenecarboxamide | HCID 59402712 | 3% |
Reaction Steps
Synthesised from 2,6-difluoro-3-hydroxybenzenecarboxamide and [5-(trifluoromethyl)-1-benzothiophen-2-yl]methanol according to Method C, scheme 3. Yield 3%, mp 150-152° C., HPLC-MS (method 1): m/z 386 [M−H]−, Rt=4.39 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088791B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-8bac5759a7f84b49a138979ba3796918 |
| Source note | uspto-grants-2012_01 |