HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-6-methylbenzothiazole → 2,6-Difluoro-3-[(6-methyl-1,3-benzothiazol-2-yl)methoxy]benzenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-6-methylbenzothiazole | HCID 17335 | — |
| Reactant | 3-(Cyanomethoxy)-2,6-difluorobenzenecarboxamide | HCID 59402804 | — |
| Product | 2,6-Difluoro-3-[(6-methyl-1,3-benzothiazol-2-yl)methoxy]benzenecarboxamide | HCID 46237268 | 17% |
Reaction Steps
Synthesised from 6-methyl-1,3-benzothiazol-2-amine and 3-(cyanomethoxy)-2,6-difluorobenzene carboxamide, according to Method K, scheme 26. Yield 17% (second step), HPLC-MS (method 1): m/z 335 [M+H]+, Rt=3.70 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088791B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-05ae5082ea0646049d140347e5df9264 |
| Source note | uspto-grants-2012_01 |