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HRID415877

反应详情

EQUATION

反应方程式

HRID 415877 的结构方程式

REACTANTS

反应物

2
结构：NOCc1ccccc1
HCID102313

O-Benzylhydroxylamine

C7H9NO

结构：CC(C)(C)OC(=O)N1CC=C[C@H]1C(=O)O
HCID688391

Boc-3,4-Dehydro-L-proline

C10H15NO4

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC=C[C@H]1C(=O)NOCc1ccccc1
HCID59162856

未命名化合物

收率 86%

PROCEDURE

实验过程

(S)-tert-Butyl 2-(benzyloxycarbamoyl)-2,5-dihydro-1H-pyrrole-1-carboxylate is prepared from (S)-1-(tert-butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid (Boc-3,4-dehydro-proline) and O-benzylhydroxylamine following Method G (yield=86%). 1H NMR (300 MHz, CHCl3) δ 9.38 (s, 0.5H), 8.46 (s, 0.5H), 7.52-7.22 (m, 5H), 6.01-5.77 (m, 2H), 5.04-4.79 (m, 3H), 4.38-3.99 (m, 2H), 1.43 (s, 9H).