(2-Iodo-5-methylphenyl)methanol → (5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanol

HRID 41592Notes

Reaction equation

HRID 41592 reaction equation
I[C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[CH2:9][OH:10].[NH:11]1[CH:15]=[CH:14][N:13]=[N:12]1>>[CH3:8][C:5]1[CH:6]=[CH:7][C:2]([N:12]2[N:13]=[CH:14][CH:15]=[N:11]2)=[C:3]([CH2:9][OH:10])[CH:4]=1

Participants

3

Reactant 2

HCID 44238586(2-Iodo-5-methylphenyl)methanolHCID 178418936HCID 178418936, compound

Product 1

HCID 67250917(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanol

Procedure

The title compound was synthesized in analogy to the procedure described for building block K11 from (2-iodo-5-methylphenyl)methanol [220991-50-4] and 1H-1,2,3-triazole.

Sources & evidence

ORD record
ord-c19bfbd54fce4716aac530d7c6be0b88
Source dataset
uspto-grants-2013_09
Patent number
US08530648B2

Reaction notes

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