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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 415994Generated: October 25, 2026

4-(Trifluoromethyl)piperidine hydrochloride → HCID 178460985, compound

https://huagongshe.com/reaction/415994

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)piperidine hydrochlorideHCID 16218160—
ReactantHCID 178460988HCID 178460988—
ProductHCID 178460985HCID 17846098551%

Reaction Steps

Prepare the title compound in a 51% yield by coupling procedure 1 starting from 3′,5′-dichloro-4′-[(R)-2-oxo-trans-1-(4-triisopropylsilanyloxy-cyclohexyl)-pyrrolidin-3-ylmethyl]-biphenyl-4-carboxylic acid and 4-trifluoromethyl-piperidine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088776B2
Source datasetuspto-grants-2012_01
ORD IDord-7d7fba68ceb14557ba399a4c16f3424c
Source noteuspto-grants-2012_01