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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416034Generated: October 25, 2026

Benzene, 1-bromo-4-(trifluoromethyl)- → 1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one

https://huagongshe.com/reaction/416034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-bromo-4-(trifluoromethyl)-HCID 67872—
Reactant(5-Acetylthiophen-2-yl)boronic acidHCID 4143377—
Product1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-oneHCID 4191494—

Reaction Steps

1-(5-(4-(Trifluoromethyl)phenyl)thien-2-yl)ethanone is prepared from 5-acetyl-2-thiopheneboronic acid and 4-bromobenzotrifluoride according to general procedure A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-be740753cf6d45d28e2d8b1bd077f730
Source noteuspto-grants-2012_01