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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416036Generated: October 25, 2026

1-Bromo-4-(trifluoromethoxy)benzene → 1-(5-(4-(Trifluoromethoxy)phenyl)thien-2-yl)ethanone

https://huagongshe.com/reaction/416036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-(trifluoromethoxy)benzeneHCID 521008—
Reactant(5-Acetylthiophen-2-yl)boronic acidHCID 4143377—
Product1-(5-(4-(Trifluoromethoxy)phenyl)thien-2-yl)ethanoneHCID 59180351—

Reaction Steps

1-(5-(4-(Trifluoromethoxy)phenyl)thien-2-yl)ethanone is prepared from 5-acetyl-2-thiopheneboronic acid and 1-bromo-4-(trifluoromethoxy)benzene according to general procedure A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-f2bdb42370b145aa8fc331e1d5ce3b3a
Source noteuspto-grants-2012_01