HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-hydroxybenzaldehyde → 3-(3-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-hydroxybenzaldehyde | HCID 17022 | — |
| Reactant | 1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one | HCID 4191494 | — |
| Product | 3-(3-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one | HCID 66623921 | — |
Reaction Steps
3-(3-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)ethanone and 3-chloro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is purified by silica-gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088819B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-c98f3dcf1bd24a1f916cd93fc68d8e58 |
| Source note | uspto-grants-2012_01 |