HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-hydroxybenzaldehyde → 3-(2-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl) phenyl)thien-2-yl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-hydroxybenzaldehyde | HCID 185363 | — |
| Reactant | 1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one | HCID 4191494 | — |
| Product | 3-(2-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl) phenyl)thien-2-yl)prop-2-en-1-one | HCID 66623692 | — |
Reaction Steps
3-(2-Chloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl) phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)ethanone and 2-chloro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is purified by silica-gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088819B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-8b8c3d7666dc4054980c2d26ae548ae0 |
| Source note | uspto-grants-2012_01 |